Heracleum persicum

The genus Heracleum comprises over 120 species and is among the largest genera within the Apiaceae family, widely distributed across the Northern Hemisphere, primarily in Asia and the Eurasian region.

Hogweeds are typically tall or dwarf monocarpic perennial herbs. They feature simple, lobed, or pinnate leaves—sometimes biternate—which may be hairy or glabrous. Their inflorescences consist of umbelliform cymes. Flowers have symmetrical or zygomorphic white, greenish-white, or pale pink petals. Fruits are dry, flattened, spiny or small oval glabrous two-winged mericarps.

Golpar, or Persian hogweed (Heracleum persicum), is a perennial herb generally growing 50–120 cm tall, with straight red-brown stems densely hairy at the base. Leaves are alternate with blunt-toothed margins, glabrous, and pinnate. Flowers are pale white, each with five petals and five stamens. Fruits are ridged schizocarps, obovate in shape.

Heracleum species—especially H. persicum—are traditionally significant medicinal plants as well as culinary spices and aromatherapy agents worldwide. In Scandinavian countries, it is known as “Tromsøpalme,” and in Germany as “Persischer Bärenklau.” Golpar is traditionally used to treat ailments including flatulence and stomachache, and is recognized for therapeutic effects on epilepsy, pain, and infections [1].

Golpar also has a rich culinary history in West Asia, used as a vegetable, an anise-like flavored tea, and incense (via burning leaves and fruits). Young stems are utilized for pickling, and fruits serve as spices or flavoring ingredients in various foods. Other Heracleum species are popular as teas in Canada, liqueurs in France, food flavorings in Britain and Southeast Asia, and edible vegetables in China [2–4]. Scientific studies have reported Golpar and its essential oil exhibiting antimicrobial, antifungal, anti-inflammatory, analgesic, hepatoprotective, and antioxidant properties.

Heracleum persicum contains multiple classes of natural compounds, including volatile constituents (aliphatic esters, carbonyls, phenylpropenes, and terpenes) and nonvolatile compounds (flavonoids, furanocoumarins, tannins, and alkaloids).

Its essential oil predominantly features four categories of compounds: monoterpenes, aliphatic esters, carbonyl compounds, and phenylpropenes [1].

Notably high levels of aliphatic esters are found in aerial parts and fruits, including hexyl butyrate (10%–65.6%), octyl acetate (7.5%–40.8%), hexyl isobutyrate (0.7%–9.1%), hexyl 2-methyl butanoate (5.2%–8.57%), dodecenyl acetate (7.81%), and octyl butyrate (0.9%–6.6%). Additional reported compounds include terpenoids such as α-bergamotene, terpinolene, γ-terpinene, limonene (trace), pulegone, ρ-cymene (trace), β-pinene, (E)-β-ocimene (trace), and linalool (trace). Sesquiterpenes (spathulenol, viridiflorol, α-farnesene, α-caryophyllene) and phenylpropenes (trans-anethole, cis-anethole, estragole, and myristicin) are also significant constituents [5].

**Disclaimer: This content is for informational purposes only. It is not intended to provide medical advice or to replace consultation with a qualified healthcare professional.

Chemical Composition (%) some of Heracleum spp. essential oil from Europe and Asia:

 

Poland

Iran

n-Octyl butanoate

8.88

9.98

n-Octyl acetate

19.92

22

n-Octanol

10.3

3.63

Hexyl butanoate

2-8

15-26

n-Hexyl acetate

5-7

1-3

Applications and Benefits Across Various Industries:

    1- Pharmaceutical Industry

Heracleum persicum essential oil demonstrates broad-spectrum antimicrobial activity against bacteria and fungi, with Minimum Inhibitory Concentrations (MICs) ranging from below 62.50 μg/mL to 6.25 mg/mL. It shows potent anticancer effects, including inhibition of ovarian cancer cells (IC50 = 12.08 μg/mL) and significant tumor reduction (57.16% at 12 mg/mL). Cardiovascular benefits include lipid profile improvement by reducing triglycerides, total cholesterol, and LDL-cholesterol, while increasing HDL-cholesterol, comparable to lovastatin. The oil also exhibits analgesic and anti-inflammatory properties, supporting pain and inflammation management. Its antioxidant activity promotes immune function and cellular health, and it supports gastrointestinal health by improving intestinal function and nutrient absorption. Additionally, it may have antiepileptic potential relevant to neurological therapy.

    2- Cosmetic Industry

In cosmetics, H. persicum essential oil’s antioxidant properties may protect skin against aging and oxidative damage. Its antimicrobial activity allows it to serve as a natural preservative, enhancing product shelf life and safety. The ester-rich composition imparts a fruity, pleasant aroma suitable for skincare and personal care formulations. Anti-inflammatory properties may reduce redness, irritation, and acne, making it valuable for sensitive or problematic skin products.

    3- Food Industry

The antimicrobial effects of H. persicum essential oil improve food preservation and safety by inhibiting pathogens such as Escherichia coli and Listeria monocytogenes. Its rich ester and terpene content imparts a distinctive fruity and aromatic flavor, serving as a natural flavoring agent. This dual function supports clean-label foods with reduced synthetic additives.

    4- Fragrance Industry

The high ester content provides H. persicum essential oil with a sweet, fresh, and fruity aroma, ideal for perfumes and scented personal care products. Compounds like hexyl butanoate and octyl acetate contribute to its appealing fragrance profile. Its antimicrobial properties also suggest potential as a natural preservative in fragrance formulations.

    5- Nutraceutical Industry

In nutraceuticals, H. persicum essential oil’s cardiovascular benefits, including cholesterol-lowering effects akin to lovastatin, position it as a promising ingredient in natural supplements. Its antioxidant and anticancer properties may enhance immune support formulations, while its anti-inflammatory and analgesic effects support natural pain relief products, making it a multifunctional component in health supplements.

 

References

1- Z. Majidi and S. S. J. J. o. i. m. Lamardi,  2018, 16, 223.

2- T. Radjabian, A. Salimi, N. J. C. Rahmani and biodiversity,  2014, 11, 1945.

3 - L. W. Li Wei, C. L. Chen LinLin, W. C. Wu Chun and X. J. Xin JiaYing, 2013.

4- J. A. Johnson, D. Webster and C. A. J. J. o. e. Gray,  2013, 147, 232.

5- M. B. Bahadori, L. Dinparast, G. J. C. R. i. F. S. Zengin and F. Safety,  2016, 15, 1018. 

Documents

To Access Technical Document, Please LOGIN First